产品货号：
Z16662
中文名称：
GPR3抗体
英文名称：
Anti-GPR3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GPR3 Antibody |
| 指标别名 | ACCA,ACCA orphan receptor,G protein coupled receptor 3,GPR3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | GPR3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GPR3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human GPR3.The immunogen is located within the last 50 amino acids of GPR3. |
| 计算分子量 | 35kDa |
| 成分 | GPR3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GPR3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | GPR3,also known as ACCA,is a G-protein coupled receptor that constitutively activates adenylate cyclase and is highly expressed in the central nervous system.Overexpression of GPR3 stimulates the production of amyloid-beta peptide (Abeta),the deposition of which is one of the pathological hallmarks of Alzheimer 's disease (AD),while the ablation of GPR3 prevented the accumulation of Abeta in vitro and in an AD mouse model.This is of particular interest because of the proximity of a reported candidate Alzheimer 's disease (AD) locus,suggesting that GPR3 may be a potential therapeutic target for the treatment of AD.GPR3 has also been shown to block the proliferation of cerebellar granule cell precursors (GCP) during postnatal development by inhibiting the Shh-induced proliferation of GCP,indicating that GPR3 activation may represent one of the signals that triggers the postnatal cell cycle exit and terminal differentiation of GPCs. |
| Uniprot ID | P46089 |
| 基因名全称 | G protein-coupled receptor 3 |
| 蛋白名全称 | G protein-coupled receptor 3 |
| 推荐稀释比 | GPR3 antibody can be used for detection of GPR3 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索：GPR3抗体，GPR3多抗，Anti-GPR3 Antibody